The Tilopa 50L is certainly suitable for carry-on purposes with air travel. Many of our customers have successfully used the Tilopa as a carry-on while traveling. However, the results will vary depending on the airline, plane size, and how the bag is packed. As always, the loaded camera insert can be removed from the pack and hand carried if the airline requires the pack to be checked in. Other users have successfully carried their larger SHINN 80L backpacks on planes. With this in mind, the f-stop Tilopa 50L is relatively "carry-on" friendly.